Beat Childhood Cancer Specimen Banking and Data Registry
Specimen Banking With Clinical and Genomic Data Registry With the Establishment of Tumor Models for Pediatric Cancers
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Clinical Trial Information
Trial Contact: Armatti, Julie M; Parker, Melanie; Torrescano, Tanner; Frankos, Marie
Trial Phone: 321-843-5284 ; 321-843-1036 ; 321-841-8271 ; 321-842-8738
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IRB No: 24.080.06
Protocol Abbrev: BCC-BIO-001
Principal Investigator: Jaime C Gonzalez, MD
Age Group: Pediatric; Adult
ClinicalTrials.gov ID: NCT04715178
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Objective
Create a data registry of clinical and molecular/genomic data from cancer patients who may have undergone biopsy or surgical resection for clinical care to better understand the relationship between genomic and molecular information and clinical outcomes.
a. Define genomic landscape of pediatric cancers through the determination of the number and types of genomic alterations within tumor types/subtypes, across tumor types, and tumor evolution over time.
b. Evaluate the rate of actionable genomic alternations resulting in associated targeted therapies relative to all actionable genomic alterations.
c. Evaluate the correlation of baseline genomic alterations with clinical outcome.