Beat Childhood Cancer Specimen Banking and Data Registry
Specimen Banking With Clinical and Genomic Data Registry With the Establishment of Tumor Models for Pediatric Cancers
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Clinical Trial Information
Trial Contact: Armatti, Julie M; Parker, Melanie; Torrescano, Tanner; Frankos, Marie; Jones, Jamie; Singh, Sarah H
Trial Phone: 321-843-5284 ; 321-843-1036 ; 321-841-8271 ; 321-842-8738 ; 3218412008 ; 321.841.7561
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IRB No: 24.080.06
Protocol Abbrev: BCC-BIO-001
Principal Investigator: Jaime C Gonzalez, MD
Age Group: Pediatric; Adult
ClinicalTrials.gov ID: NCT04715178
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Objective
Create a data registry of clinical and molecular/genomic data from cancer patients who may have undergone biopsy or surgical resection for clinical care to better understand the relationship between genomic and molecular information and clinical outcomes.
a. Define genomic landscape of pediatric cancers through the determination of the number and types of genomic alterations within tumor types/subtypes, across tumor types, and tumor evolution over time.
b. Evaluate the rate of actionable genomic alternations resulting in associated targeted therapies relative to all actionable genomic alterations.
c. Evaluate the correlation of baseline genomic alterations with clinical outcome. -
Key Eligibility
Inclusion Criteria:
No age restrictions
Subjects that fit into one of the following categories:
1. Subjects with suspected or confirmed cancers of childhood, adolescence, or young adulthood.
2. Survivors of a cancer of childhood, adolescence, or young adulthood (> 6 months off last therapy for cancer)
3. Subjects with a disease-matched condition
4. Healthy volunteers- including any participants with medical conditions that are not disease-matched.
Written informed consent in accordance with institutional and FDA guidelines must be obtained from all subjects (or subjects' legal representative).
