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Beat Childhood Cancer Specimen Banking and Data Registry

Specimen Banking With Clinical and Genomic Data Registry With the Establishment of Tumor Models for Pediatric Cancers

  • Clinical Trial Information

    Trial Contact: Armatti, Julie M; Parker, Melanie; Torrescano, Tanner; Frankos, Marie

  • IRB No: 24.080.06

    Protocol Abbrev: BCC-BIO-001

    Principal Investigator: Jaime C Gonzalez, MD

    Age Group: Pediatric; Adult

    ClinicalTrials.gov ID: NCT04715178

  • Objective

    Create a data registry of clinical and molecular/genomic data from cancer patients who may have undergone biopsy or surgical resection for clinical care to better understand the relationship between genomic and molecular information and clinical outcomes.
    a. Define genomic landscape of pediatric cancers through the determination of the number and types of genomic alterations within tumor types/subtypes, across tumor types, and tumor evolution over time.
    b. Evaluate the rate of actionable genomic alternations resulting in associated targeted therapies relative to all actionable genomic alterations.
    c. Evaluate the correlation of baseline genomic alterations with clinical outcome.