Treatment of Germ Cell Tumor w/Chemo and Radiation

Phase 2 Trial of Response-Based Radiation Therapy for Patients with Localized Central Nervous System Germ Cell Tumors (CNS GCT): A Groupwide Phase II Study

November 22, 2017

  • Clinical Trial Information

    Trial Contact: El-Shami, Jessica

    Trial Phone: 321.841.3837

  • IRB No: ACNS1123

    Principal Investigator: Vincent F. Giusti, MD

    Sub Investigators: AguilarBonilla, Ana MD; Eslin, Don MD; Martin, Rebecca, ARNP; Pope, Michele ARNP; Smith, Amy MD; Story, Allison ARNP; Sullivan, Kelly ARNP; Sutphin, Robert MD; Wieber, Laura ARNP; Levy, Alejandro MD

    Phase: Drug: Phase II

    Age Group: Pediatric

    Secondary Protocol No: ACNS1123

    Treatment: Surgery; Radiation

    Applicable Disease Sites: Brain

    Therapies Involved: Procedure: surgery Radiation: 3-D conformal radiation therapy & IMRT Drug: carboplatin Drug: etoposide Drug: ifosfamide

    ClinicalTrials.gov ID: NCT01602666

  • Objective

    This trial studies how well chemotherapy and radiation therapy work in treating younger patients with newly diagnosed central nervous system germ cell tumors.

  • Key Eligibility

    Ages Eligible for Study: 3 Years to 21 Years; Genders Eligible for Study: Both; Accepts Healthy Volunteers: No